SNP genotyping
SNP allele determination by real-time PCR
The SNP-Screen family is used to determine specific single-nucleotide polymorphisms by real-time PCR. The current catalog contains 291 active NP products; the most useful discovery path is by gene, rs identifier, or variant name.
The page is organized around the analytical task: select a specific SNP, perform allele-specific real-time PCR, and obtain a genotype/allele result. Clinical meaning is presented only when directly supported by the intended use and current documentation of a specific product.
What the page supports
- find an assay by gene or rs identifier;
- select an active SNP-Screen NP product;
- determine an SNP allele by real-time PCR;
- open verified product documentation;
- verify instrument compatibility for a specific assay;
- discuss development of a new SNP real-time PCR assay.
Marker-to-genotype analytical route
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01 →DNA
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02 →Marker selection
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03 →Allele-specific real-time PCR
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04Allele / genotype result RESULT
Methods and technology support
Method
SNP-Screen determines SNP alleles by real-time PCR using a pair of allele-specific probes. Instrument compatibility remains specific to each assay.
Find by marker
Each entry can expose the current product name and model and, where supported, a gene and rs identifier. This supports a large portfolio without manually featuring clinically sensitive variants.
Find an assay by marker
The current SNP-Screen range contains 291 active NP products. Assays can be found by gene, rs identifier, and variant name.
Reagent kit for determination of polymorphism C3435T gene MDR1 (rs1045642)
Reagent kit for determination of polymorphism G3730A (G9041A) gene VKORC1 (vitamin K epoxide reductase complex, subunit 1) (rs7294)
Reagent kit for determination of polymorphism C1173T (C6484T) gene VKORC1 (vitamin K epoxide reductase complex, subunit 1) (rs9934438)
Reagent kit for determination of polymorphism G1639A (G3673A) gene VKORC1 (rs9923231)
Reagent kit for determination of polymorphism Asp85Tyr gene UGT2B15 (URIDINE DIPHOSPHATE GLYCOSYLTRANSFERASE 2 FAMILY, MEMBER B15, rs1902023)
Reagent kit for determination of polymorphism T/C gene GSTA4 (glutathione S-transferase alpha 4) rs3756980
Kit for determination of the CYP2D6 c.2988G>A polymorphism, allele CYP2D6*41 (rs28371725)
Reagent kit for determination of polymorphism OCT1 (organic cation transporter member 1)
Reagent kit for determination of polymorphism Tyr94 (C282T) gene NAT2 (rs1041983)
Reagent kit for determination of polymorphism Ile114Thr (T341S) gene NAT2 (N-acetyltransferase 2) (rs1801280)
Reagent kit for determination of polymorphism C481T (rs1799929) gene NAT2 (N-acetyltransferase 2)
Reagent kit for determination of polymorphism G590A (rs1799930) gene NAT2 (N-acetyltransferase 2)
Show current assortment291
Move from the task to concrete resources
SNP-Screen family reference
Open family↗Single-Nucleotide Polymorphisms (SNPs) and Their Significance
Open material↗For analysis SNP
Open material↗User Training
Practical user training for working with reagents, protocols and laboratory scenarios.
Open service↗Result interpretation
An SNP-genotyping result determines an allele or genotype. By itself, it does not establish diagnosis, disease risk, prognosis, treatment response, drug selection, or dosing. Medical interpretation requires the intended use and documentation of the specific assay.
Primary actions
“Find an SNP by gene or rs”, “Select an assay”, “Check compatibility”, “Discuss SNP assay development.”
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