SNP genotyping
SNP allele determination by real-time PCR
The SNP-Screen family is used to determine specific single-nucleotide polymorphisms by real-time PCR. The current catalog contains 291 active NP products; the most useful discovery path is by gene, rs identifier, or variant name.
The page is organized around the analytical task: select a specific SNP, perform allele-specific real-time PCR, and obtain a genotype/allele result. Clinical meaning is presented only when directly supported by the intended use and current documentation of a specific product.
What the page supports
- find an assay by gene or rs identifier;
- select an active SNP-Screen NP product;
- determine an SNP allele by real-time PCR;
- open verified product documentation;
- verify instrument compatibility for a specific assay;
- discuss development of a new SNP real-time PCR assay.
Marker-to-genotype analytical route
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01 →DNA
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02 →Marker selection
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03 →Allele-specific real-time PCR
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04Allele / genotype result RESULT
Methods and technology support
Method
SNP-Screen determines SNP alleles by real-time PCR using a pair of allele-specific probes. Instrument compatibility remains specific to each assay.
Find by marker
Each entry can expose the current product name and model and, where supported, a gene and rs identifier. This supports a large portfolio without manually featuring clinically sensitive variants.
Find an assay by marker
The current SNP-Screen range contains 291 active NP products. Assays can be found by gene, rs identifier, and variant name.
Reagent kit for determination of polymorphism Gln279Arg gene MMP9 (matrix metallopeptidase 9) (rs17576)
Kit for determination of polymorphism 4682G>A gene TNF (tumor necrosis factor) (rs1800629)
Kit for determination of polymorphism Ala16Val (C47T) gene SOD2 (rs4800)
Reagent kit for determination of polymorphism T/C gene GSTA4 (glutathione S-transferase alpha 4) rs3756980
Kit for determination of polymorphism Asp299Gly gene TLR4 (rs4986790) (toll-like receptor 4)
Reagent kit for determination of polymorphism A8595G gene TLR4 (toll-like receptor 4) rs1927911
Reagent kit for determination of polymorphism C14510A gene SOD2 (superoxide dismutase 2, mitochondrial) rs2758330
Reagent kit for determination of polymorphism C14405T gene FAS (Fas cell surface death receptor) rs1159120
Reagent kit for determination of polymorphism T(-3499)C gene FOXP3 (forkhead box P3) rs3761547
Reagent kit for determination of polymorphism C(-1306)T gene MMP2 (rs243865)
Reagent kit for determination of polymorphism G/T gene STAT4 (rs7574865)
Kit for determination of polymorphism T6000A gene IFNG (rs2430561)
Show current assortment291
Move from the task to concrete resources
SNP-Screen family reference
Open family↗Single-Nucleotide Polymorphisms (SNPs) and Their Significance
Open material↗For analysis SNP
Open material↗User Training
Practical user training for working with reagents, protocols and laboratory scenarios.
Open service↗Result interpretation
An SNP-genotyping result determines an allele or genotype. By itself, it does not establish diagnosis, disease risk, prognosis, treatment response, drug selection, or dosing. Medical interpretation requires the intended use and documentation of the specific assay.
Primary actions
“Find an SNP by gene or rs”, “Select an assay”, “Check compatibility”, “Discuss SNP assay development.”
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