Articles tagged “Probes for Real-Time PCR”

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Probes for Real-Time PCR

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Lineynye probes

linear probe, labeled by ends with different relative arrangement dyes: 1) Fluorophore — oligonucleotide — quencher; 2) quencher — oligonucleotide — Fluorophore.
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Probes for real-time PCR

Real-time PCR is a standard method for DNA and RNA analysis. Fluorescent probes are oligonucleotides carrying a fluorophore and a fluorescence quencher; their sequence is selected so that the probe anneals between the forward and reverse primers.
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Fluorescence quenchers

Dabsyl is used as a quencher for fluorophores with emission maxima from 450 to 550 nm and is commonly incorporated into oligonucleotide probes for quantitative real-time PCR.
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